Comparative RNA Sequence and Structure Analysis

Purpose

Comparative sequence analysis has been successfully utilized to identify RNA structures that are common to different families of properly aligned RNA sequences. The major goal of the project is to develop a computational foundation utilizing relational database management system to significantly enhance the comparative analysis of RNA sequences, their higher-order structures, and their evolutionary and phylogenetic relationships with one another. The scope of this project includes developing new relational database schema for storing comprehensive information about RNA sequences, developing new scalable multiple sequence alignment algorithms, and developing tools to facilitate access of the information.

Funding Source(s)

  • National Institute of Health (NIH)
Related Link(s)
Weijia Xu

Research Associate
xwh@tacc.utexas.edu | 512-475-9411