Ethan Ho

Ethan Ho

Computational Biologist

Life Sciences Research Acceleration


Ethan Ho earned a B.A. in Biochemistry and Molecular Biology at Reed College. His research experience includes computational, structural, and biochemical characterization of endonucleases and metalloproteins. In 2019, he joined the Life Sciences Computing group at TACC, where he promotes accessible, reproducible use of advanced computing resources in collaboration with life science researchers.

Areas of Research

Protein design and fold prediction
Genetic circuit engineering
Visualization of macromolecular structures

Current Projects

DARPA-SD2E - Synergistic Discovery and Design

Selected Publications

Riel, Asia Marie S., Rhianon K. Rowe, Ethan N. Ho, Anna-Carin C. Carlsson, Anthony K. Rappé, Orion B. Berryman, and Pui Shing Ho. "Hydrogen Bond Enhanced Halogen Bonds: A Synergistic Interaction in Chemistry and Biochemistry." Accounts of chemical research (2019).

Chacón, Kelly N., Jonathan Perkins, Zachary Mathe, Katherine Alwan, Ethan N. Ho, Melek N. Ucisik, Kenneth M. Merz, and Ninian J. Blackburn. "Trapping intermediates in metal transfer reactions of the CusCBAF export pump of Escherichia coli." Nature Communications Biology 1, no. 1 (2018): 192.

Crystal M. Vander Zanden, Ethan N. Ho, Ryan S. Czarny, Adam B. Robertson, and P. Shing Ho. "Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function." Manuscript under review.


B.A., B.S., Mathematics

University of Florida

B.A., Biochemistry and Molecular Biology

Reed College