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Researchers internationally have built one of the most comprehensive catalogs of the human transcriptome ever.

By combining complementary sequencing techniques, they have deepened our understanding of the function of known ribonucleic acid (RNA) molecules and discovered thousands of new RNAs.

Their research, published in Nature Biotechnology, is the result of more than five years of work to further unravel the complexity of the human transcriptome to study disease processes and uncover novel genes that may serve as therapeutic targets or biomarkers.

The researchers relied on TACC's Stampede2 supercomputer to prove that these genes play a role in cells and tissues and are not merely byproducts of other cellular processes.


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