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New research from UT Austin dramatically expands the number of naturally occurring versions of this system, giving researchers a wealth of potential new tools for large-scale gene editing.

A team led by Ilya Finkelstein and Claus Wilke have expanded the number of likely CASTs from about a dozen to nearly 1,500. They published their results in the journal Proceedings of the National Academy of Sciences.

Using TACC's Stampede2 supercomputer, the team combed through the world's largest database of genome fragments from microbes that have not yet been cultured in the lab or fully sequenced.


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