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Story Highlights

First time that human pre-initiation complex (PIC) modeled at near atomic-level resolution.

Cryo-electron microscopy combined with supercomputer simulations to produce new PIC model.

Key transcription factor component TFIIH structure resolved for first time.

XSEDE Stampede ran over four million core hours of molecular machine simulations.

Modeling molecular machines lays foundation for producing cures to diseases such as cancer.


Faith Singer

Communications Manager | 512-232-5771

Aaron Dubrow

Science And Technology Writer

Jorge Salazar

Technical Writer/Editor | 512-475-9411